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Chrng (GeneName), Acetylcholine receptor subunit gamma (ProteinName), ACHG_MOUSE.
Product Name:

Mouse Chrng/ Acetylcholine receptor subunit gamma ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Acrg

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Acetylcholine receptor subunit gamma
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
Mouse Chrng ELISA Kit
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Mouse Chrng ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains.


Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


Subcellular Location:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Escobar syndrome is a prenatal myasthenia caused by disruption of the acetylcholine receptor fetal gamma subunit."

[2].
"Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans."

[3].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."

[4].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[5].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."

[6].
"Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study."

[7].
"Mutations in the embryonal subunit of the acetylcholine receptor (CHRNG) cause lethal and Escobar variants of multiple pterygium syndrome."

[8].
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."

[9].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[10].
"Primary structure of the human muscle acetylcholine receptor. cDNA cloning of the gamma and epsilon subunits."
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