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Chrnd (GeneName), Acetylcholine receptor subunit delta (ProteinName), ACHD_MOUSE.
Product Name:

Mouse Chrnd/ Acetylcholine receptor subunit delta ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Acrd

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Acetylcholine receptor subunit delta
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
Mouse Chrnd ELISA Kit
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Mouse Chrnd ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains.


Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


Subcellular Location:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Association of the gene encoding the delta-subunit of the muscle acetylcholine receptor (CHRND) with acquired autoimmune myasthenia gravis."

[2].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."

[3].
"Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans."

[4].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."

[5].
"Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis."

[6].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[7].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."

[8].
"Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders."

[9].
"Congenital myasthenia-related AChR delta subunit mutation interferes with intersubunit communication essential for channel gating."

[10].
"Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study."
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