CHRND (GeneName), Acetylcholine receptor subunit delta (ProteinName), ACHD_BOVIN.
Product Name:
Bovine CHRND/ Acetylcholine receptor subunit delta ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Specificity:
Natural and recombinant bovine Acetylcholine receptor subunit delta
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains.
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location:
Cell junction
Synapse
Postsynaptic cell membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Association of the gene encoding the delta-subunit of the muscle acetylcholine receptor (CHRND) with acquired autoimmune myasthenia gravis."
[2].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."
[3].
"Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans."
[4].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."
[5].
"Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis."
[6].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
[7].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."
[8].
"Acetylcholine receptor pathway mutations explain various fetal akinesia deformation sequence disorders."
[9].
"Congenital myasthenia-related AChR delta subunit mutation interferes with intersubunit communication essential for channel gating."
[10].
"Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study."
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