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CHRNB1 (GeneName), Acetylcholine receptor subunit beta (ProteinName), ACHB_BOVIN.
Product Name:

Bovine CHRNB1/ Acetylcholine receptor subunit beta ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Specificity:
Natural and recombinant bovine Acetylcholine receptor subunit beta
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
Bovine CHRNB1 ELISA Kit
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Bovine CHRNB1 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains.


Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


Subcellular Location:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence."

[2].
"Mutations Causing Slow-Channel Myasthenia Reveal That a Valine Ring in the Channel Pore of Muscle AChR is Optimized for Stabilizing Channel Gating."

[3].
"Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans."

[4].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."

[5].
"Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerstr?m test for nicotine dependence."

[6].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[7].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."

[8].
"Examination of the nicotine dependence (NICSNP) consortium findings in the Iowa adoption studies population."

[9].
"No evidence for association between 19 cholinergic genes and bipolar disorder."

[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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