Chrnb3 (GeneName), Neuronal acetylcholine receptor subunit beta-3 (ProteinName), ACHB3_RAT.
Product Name:
Rat Chrnb3/ Neuronal acetylcholine receptor subunit beta-3 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Acrb3
Detection Method:
ELISA
Specificity:
Natural and recombinant rat Neuronal acetylcholine receptor subunit beta-3
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Neuronal AChR seems to be composed of two different types of subunits: alpha and beta.
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location:
Cell junction
Synapse
Postsynaptic cell membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Database link
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence."
[4].
"Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans."
[5].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."
[6].
"Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerstr?m test for nicotine dependence."
[7].
"Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample."
[8].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
[9].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
[10].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."
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