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CHRNA1 (GeneName), Acetylcholine receptor subunit alpha (ProteinName), ACHA_BOVIN.
Product Name:

Bovine CHRNA1/ Acetylcholine receptor subunit alpha ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Specificity:
Natural and recombinant bovine Acetylcholine receptor subunit alpha
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
Bovine CHRNA1 ELISA Kit
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Bovine CHRNA1 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains.


Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


Subcellular Location:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Differential expression of human nicotinic acetylcholine receptor alpha subunit variants in muscle and non-muscle tissues."

[2].
"The human muscle nicotinic acetylcholine receptor alpha-subunit exist as two isoforms: a novel exon."

[3].
"Association of CHRN genes with "dizziness" to tobacco."

[4].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."

[5].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[6].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[7].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."

[8].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[9].
"Examination of the nicotine dependence (NICSNP) consortium findings in the Iowa adoption studies population."

[10].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."
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