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首页  >  酶联免疫试剂盒  >  Human CHRNA9 ELISA Kit
CHRNA9 (基因名), Neuronal acetylcholine receptor subunit alpha-9 (蛋白名), ACHA9_HUMAN.
产品名称:

Human CHRNA9/ Neuronal acetylcholine receptor subunit alpha-9 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Nicotinic acetylcholine receptor subunit alpha-9, NACHR alpha-9, NACHRA9

检测方法:
ELISA
特异性:
Natural and recombinant human Neuronal acetylcholine receptor subunit alpha-9
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Neurosciences
Human CHRNA9 ELISA Kit
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Human CHRNA9 ELISA Kit
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产品说明书


通用注释


亚单元:
Can form homo- or heterooligomeric channels in conjunction with CHRNA10 (PubMed:11752216). The native outer hair cell receptor may be composed of CHRNA9-CHRNA10 heterooligomers. Interacts with the alpha-conotoxon RgIA (PubMed:22774872).


功能:
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed:11021840).


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


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