CHRNA9 (GeneName), Neuronal acetylcholine receptor subunit alpha-9 (ProteinName), ACHA9_CHICK.
Product Name:
Chicken CHRNA9/ Neuronal acetylcholine receptor subunit alpha-9 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Nicotinic acetylcholine receptor subunit alpha-9, NACHR alpha-9
Detection Method:
ELISA
Specificity:
Natural and recombinant chicken Neuronal acetylcholine receptor subunit alpha-9
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
N/A
Function:
Ionotropic receptor that may play a role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane.
Subcellular Location:
Cell junction
Synapse
Postsynaptic cell membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function."
[2].
"A novel human nicotinic receptor subunit, alpha10, that confers functionality to the alpha9-subunit."
[3].
"Chromosome location and characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) gene."
[4].
"Crystal structures of free and antagonist-bound states of human α9 nicotinic receptor extracellular domain."
[5].
"Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA."
[6].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."
[7].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
[8].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."
[9].
"No evidence for association between 19 cholinergic genes and bipolar disorder."
[10].
"Why do young women smoke? I. Direct and interactive effects of environment, psychological characteristics and nicotinic cholinergic receptor genes."
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