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Home  >  ELISA Kit  >  Mouse Chrna6 ELISA Kit
Chrna6 (GeneName), Neuronal acetylcholine receptor subunit alpha-6 (ProteinName), ACHA6_MOUSE.
Product Name:

Mouse Chrna6/ Neuronal acetylcholine receptor subunit alpha-6 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Nica6

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Neuronal acetylcholine receptor subunit alpha-6
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
Mouse Chrna6 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Neuronal AChR seems to be composed of two different types of subunits: alpha and non-alpha (beta). Interacts with LYPD6.


Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


Subcellular Location:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits."

[2].
"Functional interaction between Lypd6 and nicotinic acetylcholine receptors."

[3].
"Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior."

[4].
"Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans."

[5].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."

[6].
"Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerstr?m test for nicotine dependence."

[7].
"Prenatal exposure to maternal cigarette smoking interacts with a polymorphism in the alpha6 nicotinic acetylcholine receptor gene to influence drug use and striatum volume in adolescence."

[8].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[9].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."

[10].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."
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