CHRNA6 (GeneName), Neuronal acetylcholine receptor subunit alpha-6 (ProteinName), ACHA6_CHICK.
Product Name:
Chicken CHRNA6/ Neuronal acetylcholine receptor subunit alpha-6 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Specificity:
Natural and recombinant chicken Neuronal acetylcholine receptor subunit alpha-6
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Neuronal AChR seems to be composed of two different type of subunits: alpha and non-alpha (also called beta). A functional receptor seems to consist of two alpha-chains and three non-alpha chains.
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location:
Cell junction
Synapse
Postsynaptic cell membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Database link
This product has not yet been referenced specifically in any publications.
[1].
"Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits."
[4].
"Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans."
[5].
"A large-scale candidate gene association study of age at menarche and age at natural menopause."
[6].
"Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerstr?m test for nicotine dependence."
[7].
"Prenatal exposure to maternal cigarette smoking interacts with a polymorphism in the alpha6 nicotinic acetylcholine receptor gene to influence drug use and striatum volume in adolescence."
[8].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."
[9].
"Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis."
[10].
"Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes."
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