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Chrna5 (GeneName), Neuronal acetylcholine receptor subunit alpha-5 (ProteinName), ACHA5_MOUSE.
Product Name:

Mouse Chrna5/ Neuronal acetylcholine receptor subunit alpha-5 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Neuronal acetylcholine receptor subunit alpha-5
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Neurosciences
Mouse Chrna5 ELISA Kit
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Mouse Chrna5 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Neuronal AChR seems to be composed of two different types of subunits: alpha and non-alpha (beta). Interacts with LYPD6.


Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.


Subcellular Location:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans."

[2].
"Smoking cessation and variations in nicotinic acetylcholine receptor subunits alpha-5, alpha-3, and beta-4 genes."

[3].
"Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk."

[4].
"Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence."

[5].
"Why do young women smoke? V. Role of direct and interactive effects of nicotinic cholinergic receptor gene variation on neurocognitive function."

[6].
"Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1."

[7].
"A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25."

[8].
"A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence."

[9].
"Variants in nicotinic receptors and risk for nicotine dependence."

[10].
"Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking."
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