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首页  >  酶联免疫试剂盒  >  Rat Chrna10 ELISA Kit
Chrna10 (基因名), Neuronal acetylcholine receptor subunit alpha-10 (蛋白名), ACH10_RAT.
产品名称:

Rat Chrna10/ Neuronal acetylcholine receptor subunit alpha-10 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Nicotinic acetylcholine receptor subunit alpha-10, NACHR alpha-10

检测方法:
ELISA
特异性:
Natural and recombinant rat Neuronal acetylcholine receptor subunit alpha-10
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Neurosciences
Rat Chrna10 ELISA Kit
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Rat Chrna10 ELISA Kit
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产品说明书


通用注释


亚单元:
Forms heterooligomeric channels in conjunction with CHRNA9. The native outer hair cell receptor may be composed of CHRNA9-CHRNA10 heterooligomers. Interacts with the conotoxin GeXXA (PubMed:26395518). Interacts with the alpha-conotoxin RgIA (PubMed:25740413).


功能:
Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this leads to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.


亚细胞位置:
Cell junction Synapse Postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein


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