Acer3 (GeneName), Alkaline ceramidase 3 (ProteinName), ACER3_MOUSE.
Mouse Acer3/ Alkaline ceramidase 3 ELISA Kit
AlkCDase 3, Alkaline phytoceramidase, aPHC, Aphc, Phca
Natural and recombinant mouse Alkaline ceramidase 3
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.
Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein
MAPAVDRKGY | WGPTTSTLDW | CEENYVVTLF | VAEFWNTVSN | LIMIIPPIFG |
AIQGIRDRLE | KRYIAAYLAL | TVVGMGSWCF | HMTLKYEMQL | LDELPMIYSC |
CIFVYCMFEC | FKTKSSINYH | LLFTLFLYSL | TVTTIYLKVK | EPIFHQVMYG |
MLVFTLVLRS | IYIVTWVYPW | LRGLGYTSLT | VFLLGFLLWN | IDNIFCDSLR |
NFRKRVPPVL | GVTTQFHAWW | HILTGLGSYL | HILFSLYTRT | LYLRYRPKVK |
FLFGIWPAVM | FEPQRKH
This product has not yet been referenced specifically in any publications.
"Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide."
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
"Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging."
"Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate."
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
"Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy."
"ACER3 supports development of acute myeloid leukemia."
"Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis."
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