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Acer3 (GeneName), Alkaline ceramidase 3 (ProteinName), ACER3_MOUSE.
Product Name:

Mouse Acer3/ Alkaline ceramidase 3 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

AlkCDase 3, Alkaline phytoceramidase, aPHC, Aphc, Phca

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse Alkaline ceramidase 3
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Mouse Acer3 ELISA Kit
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Mouse Acer3 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
N/A


Function:
Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.


Subcellular Location:
Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein


This product has not yet been referenced specifically in any publications.

[1].
"Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide."

[2].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[3].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[4].
"Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging."

[5].
"Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate."

[6].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy."

[9].
"ACER3 supports development of acute myeloid leukemia."

[10].
"Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis."
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