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首页  >  酶联免疫试剂盒  >  Mouse Acer2 ELISA Kit
Acer2 (基因名), Alkaline ceramidase 2 (蛋白名), ACER2_MOUSE.
产品名称:

Mouse Acer2/ Alkaline ceramidase 2 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

AlkCDase 2, Acylsphingosine deacylase 3-like, Cancer-related gene liver 1 protein, CRG-L1, N-acylsphingosine amidohydrolase 3-like, Asah3l

检测方法:
ELISA
特异性:
Natural and recombinant mouse Alkaline ceramidase 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Acer2 ELISA Kit
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Mouse Acer2 ELISA Kit
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产品说明书


通用注释


亚单元:
N/A


功能:
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Unsaturated long-chain ceramides are the best substrates, saturated long-chain ceramides and unsaturated very long-chain ceramides are good substrates, whereas saturated very long-chain ceramides and short-chain ceramides were poor substrates. Inhibits the maturation of protein glycosylation in the Golgi complex, including that of integrin beta-1 (ITGB1) and of LAMP1, by increasing the levels of sphingosine. Inhibits cell adhesion by reducing the level of ITGB1 in the cell surface. May have a role in cell proliferation and apoptosis that seems to depend on the balance between sphingosine and sphingosine-1-phosphate.


亚细胞位置:
Golgi apparatus membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Alkaline ceramidase 2 regulates beta1 integrin maturation and cell adhesion."

[2].
"Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2)."

[3].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[4].
"Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P."

[5].
"DNA sequence and analysis of human chromosome 9."

[6].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[7].
"Large-scale cDNA transfection screening for genes related to cancer development and progression."

[8].
"Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response."

[9].
"Regulation of alkaline ceramidase activity by the c-Src-mediated pathway."

[10].
"Alkaline ceramidase 2 (ACER2) and its product dihydrosphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells."
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