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Acer2 (基因名), Alkaline ceramidase 2 (蛋白名), ACER2_MOUSE.
产品名称:

Mouse Acer2/ Alkaline ceramidase 2 ELISA Kit

货号:

E11204m

商标:
EIAab®
监管等级:
别名:

Acylsphingosine deacylase 3-like, Cancer-related gene liver 1 protein, N-acylsphingosine amidohydrolase 3-like, CRG-L1, AlkCDase 2, Asah3l

检测方法:
ELISA
特异性:
Natural and recombinant mouse Alkaline ceramidase 2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Acer2 ELISA Kit
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Mouse Acer2 ELISA Kit
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亚单元:
N/A


功能:
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Unsaturated long-chain ceramides are the best substrates, saturated long-chain ceramides and unsaturated very long-chain ceramides are good substrates, whereas saturated very long-chain ceramides and short-chain ceramides were poor substrates. Inhibits the maturation of protein glycosylation in the Golgi complex, including that of integrin beta-1 (ITGB1) and of LAMP1, by increasing the levels of sphingosine. Inhibits cell adhesion by reducing the level of ITGB1 in the cell surface. May have a role in cell proliferation and apoptosis that seems to depend on the balance between sphingosine and sphingosine-1-phosphate.


亚细胞位置:
Golgi apparatus membrane Multi-pass membrane protein


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