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Home  >  ELISA Kit  >  Mouse Ace2 ELISA Kit
Ace2 (GeneName), Angiotensin-converting enzyme 2 (ProteinName), ACE2_MOUSE.
Product Name:

Mouse Ace2/ Angiotensin-converting enzyme 2 ELISA Kit

Cat.#:

E1886m

Brand:
EIAab®
Regulatory Status:
Alternative:

ACE-related carboxypeptidase

Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.312-20ng/mL
Sensitivity:
0.174ng/mL
Specificity:
Natural and recombinant mouse Angiotensin-converting enzyme 2
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
Mouse Ace2 ELISA Kit
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Mouse Ace2 ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


General Annotation


Sub Unit:
Interacts with ITGB1 and the catalytically active form of TMPRSS2 (By similarity). Weakly interacts with SARS-CoV S protein.


Function:
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury.


Subcellular Location:
Cell membrane Single-pass type I membrane protein Cytoplasm Detected in both cell membrane and cytoplasm in neurons.


This product has not yet been referenced specifically in any publications.

[1].
"A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9."

[2].
"[Relationship of angiotensin-converting enzyme 2 gene polymorphisms and vulnerability to coronary heart disease in patients with type 2 diabetes mellitus]."

[3].
"Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of Captopril in women."

[4].
"Association of angiotensin-converting enzyme 2 (ACE2) gene polymorphisms with parameters of left ventricular hypertrophy in men. Results of the MONICA Augsburg echocardiographic substudy."

[5].
"Association analysis of common variants of ELN, NOS2A, APOE and ACE2 to intracranial aneurysm."

[6].
"Myocardial infarction increases ACE2 expression in rat and humans."

[7].
"Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2."

[8].
"Identification of an alternative 5'-untranslated exon and new polymorphisms of angiotensin-converting enzyme 2 gene: lack of association with SARS in the Vietnamese population."

[9].
"Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2)."

[10].
"Polymorphisms in the gene encoding angiotensin I converting enzyme 2 and diabetic nephropathy."
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