Acadsb (GeneName), Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (ProteinName), ACDSB_RAT.
Product Name:
Rat Acadsb/ Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ELISA Kit
Cat.#:
E12556r
Brand:
EIAab®
Regulatory Status:
Alternative:
SBCAD, 2-methyl branched chain acyl-CoA dehydrogenase, 2-MEBCAD, 2-methylbutyryl-coenzyme A dehydrogenase, 2-methylbutyryl-CoA dehydrogenase
Detection Method:
ELISA
Specificity:
Natural and recombinant rat Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Cardiovascular
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homotetramer.
Function:
Has greatest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl-CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent.
Subcellular Location:
Mitochondrion matrix
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Short/branched-chain acyl-CoA dehydrogenase deficiency due to an IVS3+3A>G mutation that causes exon skipping."
[2].
"Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism."
[3].
"Localization of short/branched chain acyl-CoA dehydrogenase (ACADSB) to human chromosome 10."
[4].
"Isolation and expression of a cDNA encoding the precursor for a novel member (ACADSB) of the acyl-CoA dehydrogenase gene family."
[5].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."
[6].
"Association of genetic polymorphisms of ACADSB and COMT with human hypertension."
[7].
"A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease."
[9].
"2-ethylhydracrylic aciduria in short/branched-chain acyl-CoA dehydrogenase deficiency: application to diagnosis and implications for the R-pathway of isoleucine oxidation."
[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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