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首页  >  酶联免疫试剂盒  >  Rat Accn3 ELISA Kit
Accn3 (基因名), Amiloride-sensitive cation channel 3 (蛋白名), ACCN3_RAT.
产品名称:

Rat Accn3/ Amiloride-sensitive cation channel 3 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Acid-sensing ion channel 3, ASIC3, Dorsal root ASIC, DRASIC, Asic3, Drasic

检测方法:
ELISA
特异性:
Natural and recombinant rat Amiloride-sensitive cation channel 3
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Rat Accn3 ELISA Kit
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产品说明书


通用注释


亚单元:
Homotrimer or heterotrimer with other ASIC proteins (By similarity). Interacts with STOM, LIN7B, MAGI1 and GOPC (By similarity). Interacts with DLG4 and ACCN1.


功能:
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.


亚细胞位置:
Cytoplasm Cell membrane Multi-pass membrane protein In part cytoplasmic in cochlea cells (By similarity). Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4.


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