Accn3 (GeneName), Amiloride-sensitive cation channel 3 (ProteinName), ACCN3_RAT.
Rat Accn3/ Amiloride-sensitive cation channel 3 ELISA Kit
Acid-sensing ion channel 3, ASIC3, Dorsal root ASIC, DRASIC, Asic3, Drasic
Natural and recombinant rat Amiloride-sensitive cation channel 3
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Homotrimer or heterotrimer with other ASIC proteins (By similarity). Interacts with STOM, LIN7B, MAGI1 and GOPC (By similarity). Interacts with DLG4 and ACCN1.
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties.
Cytoplasm Cell membrane Multi-pass membrane protein In part cytoplasmic in cochlea cells (By similarity). Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4.
MKPRSGLEEA | QRRQASDIRV | FASSCTMHGL | GHIFGPGGLT | LRRGLWATAV |
LLSLAAFLYQ | VAERVRYYGE | FHHKTTLDER | ESHQLTFPAV | TLCNINPLRR |
SRLTPNDLHW | AGTALLGLDP | AEHAAYLRAL | GQPPAPPGFM | PSPTFDMAQL |
YARAGHSLED | MLLDCRYRGQ | PCGPENFTVI | FTRMGQCYTF | NSGAHGAELL |
TTPKGGAGNG | LEIMLDVQQE | EYLPIWKDME | ETPFEVGIRV | QIHSQDEPPA |
IDQLGFGAAP | GHQTFVSCQQ | QQLSFLPPPW | GDCNTASLDP | DDFDPEPSDP |
LGSPRPRPSP | PYSLIGCRLA | CESRYVARKC | GCRMMHMPGN | SPVCSPQQYK |
DCASPALDAM | LRKDTCVCPN | PCATTRYAKE | LSMVRIPSRA | SARYLARKYN |
RSESYITENV | LVLDIFFEAL | NYEAVEQKAA | YEVSELLGDI | GGQMGLFIGA |
SLLTILEILD | YLCEVFQDRV | LGYFWNRRSA | QKRSGNTLLQ | EELNGHRTHV |
PHLSLGPRPP | TTPCAVTKTL | SASHRTCYLV | TRL
This product has not yet been referenced specifically in any publications.
Displaying result : 0
No feedback yet, let's comment.
Product Name *
Size Quantity Price ($) Subtotal 1 ($)
Subtotal 2: $
Size Quantity Price ($)
Do you want to be our agent and get a lower discount?
Please contact us:
Please contact us: