ACCN1 (GeneName), Amiloride-sensitive cation channel 1, neuronal (ProteinName), ACCN1_HUMAN.
Product Name:
Human ACCN1/ Amiloride-sensitive cation channel 1, neuronal ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Acid-sensing ion channel 2, ASIC2, Amiloride-sensitive brain sodium channel, Amiloride-sensitive cation channel neuronal 1, Brain sodium channel 1, BNC1, BNaC1, Mammalian degenerin homolog, ACCN, BNAC1, MDEG
Detection Method:
ELISA
Specificity:
Natural and recombinant human Amiloride-sensitive cation channel 1, neuronal
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Sequence / 3D
- Feedback Wall (0)
General Annotation
Sub Unit:
Homotrimer or heterotrimer with other ASIC proteins (By similarity). Interacts with STOM (By similarity). Interacts with PRKCABP and ACCN3.
Function:
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes.
Valid Sequence:
This product has not yet been referenced specifically in any publications.
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