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Acap1 (基因名), Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (蛋白名), ACAP1_MOUSE.
产品名称:

Mouse Acap1/ Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Centaurin-beta-1, Cnt-b1, Centb1, Kiaa0050

检测方法:
ELISA
特异性:
Natural and recombinant mouse Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Acap1 ELISA Kit
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Mouse Acap1 ELISA Kit
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通用注释


亚单元:
Banana-shaped homodimer laterally assembling into tetramers, the tetramers further pack helically onto the membrane. Interacts with GTP-bound ARF6. Interacts with third cytoplasmic loop of SLC2A4/GLUT4. Interacts with CLTC. Interacts with GULP1. Forms a complex with GDP-bound ARF6 and GULP1. Interacts with ITGB1; required for ITGB1 recycling.


功能:
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.


亚细胞位置:
Recycling endosome membrane Peripheral membrane protein Cytoplasmic side


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