Acadvl (GeneName), Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ProteinName), ACADV_MOUSE.
Mouse Acadvl/ Very long-chain specific acyl-CoA dehydrogenase, mitochondrial ELISA Kit
MVLCAD, VLCAD, Vlcad
Natural and recombinant mouse Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons.
Mitochondrion inner membrane
MQSARMTPSV | GRQLLRLGAR | SSRSTTVLQG | QPRPISAQRL | YAREATQAVL |
DKPETLSSDA | STREKPARAE | SKSFAVGMFK | GQLTIDQVFP | YPSVLSEEQA |
QFLKELVGPV | ARFFEEVNDP | AKNDALEKVE | DDTLQGLKEL | GAFGLQVPSE |
LGGLGLSNTQ | YARLAEIVGM | HDLGVSVTLG | AHQSIGFKGI | LLYGTKAQRE |
KYLPRVASGQ | ALAAFCLTEP | SSGSDVASIR | SSAIPSPCGK | YYTLNGSKIW |
ISNGGLADIF | TVFAKTPIKD | AATGAVKEKI | TAFVVERSFG | GVTHGLPEKK |
MGIKASNTSE | VYFDGVKVPS | ENVLGEVGDG | FKVAVNILNN | GRFGMAATLA |
GTMKSLIAKA | VDHATNRTQF | GDKIHNFGVI | QEKLARMAIL | QYVTESMAYM |
LSANMDQGFK | DFQIEAAISK | IFCSEAAWKV | ADECIQIMGG | MGFMKEPGVE |
RVLRDIRIFR | IFEGANDILR | LFVALQGCMD | KGKELTGLGN | ALKNPFGNVG |
LLMGEAGKQL | RRRTGIGSGL | SLSGIVHPEL | SRSGELAVQA | LDQFATVVEA |
KLVKHKKGIV | NEQFLLQRLA | DGAIDLYAMV | VVLSRASRSL | SEGYPTAQHE |
KMLCDSWCIE | AATRIRENMA | SLQSSPQHQE | LFRNFRSISK | AMVENGGLVT |
This product has not yet been referenced specifically in any publications.
"Clear correlation of genotype with disease phenotype in very-long-chain acyl-CoA dehydrogenase deficiency."
"Molecular heterogeneity in very-long-chain acyl-CoA dehydrogenase deficiency causing pediatric cardiomyopathy and sudden death."
"Very long chain acyl-coenzyme A dehydrogenase deficiency with adult onset."
"Assignment of the human mitochondrial very-long-chain acyl-CoA dehydrogenase gene (LCACD) to 17p13 by in situ hybridization."
"Cloning and characterization of human very-long-chain acyl-CoA dehydrogenase cDNA, chromosomal assignment of the gene and identification in four patients of nine different mutations within the VLCAD gene."
"Mutation analysis of very-long-chain acyl-coenzyme A dehydrogenase (VLCAD) deficiency: identification and characterization of mutant VLCAD cDNAs from four patients."
"Cloning of human very-long-chain acyl-coenzyme A dehydrogenase and molecular characterization of its deficiency in two patients."
"Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients."
"Genomic DNA organization of human mitochondrial very-long-chain acyl-CoA dehydrogenase and mutation analysis."
"Dysregulation of very long chain acyl-CoA dehydrogenase coupled with lipid peroxidation."
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