ACADS (GeneName), Short-chain specific acyl-CoA dehydrogenase, mitochondrial (ProteinName), ACADS_HUMAN.
Product Name:
Human ACADS/ Short-chain specific acyl-CoA dehydrogenase, mitochondrial ELISA Kit
Cat.#:
E10434h
Brand:
EIAab®
Regulatory Status:
Alternative:
SCAD, Butyryl-CoA dehydrogenase
Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
78-5000pg/mL
Sensitivity:
39.4pg/mL
Specificity:
Natural and recombinant human Short-chain specific acyl-CoA dehydrogenase, mitochondrial
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:

Research Area:
Cardiovascular
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homotetramer.
Function:
Introduces a double bond at position 2 in saturated acyl-CoA's of short chain length, i.e. less than 6 carbon atoms.
Subcellular Location:
Mitochondrion matrix
This product has not yet been referenced specifically in any publications.
[1].
"The 625G>A SCAD gene variant is common but not associated with increased C4-carnitine in newborn blood spots."
[2].
"The frequency of short-chain acyl-CoA dehydrogenase gene variants in the US population and correlation with the C(4)-acylcarnitine concentration in newborn blood spots."
[3].
"Role of common gene variations in the molecular pathogenesis of short-chain acyl-CoA dehydrogenase deficiency."
[4].
"Identification of four new mutations in the short-chain acyl-CoA dehydrogenase (SCAD) gene in two patients: one of the variant alleles, 511C-->T, is present at an unexpectedly high frequency in the general population, as was the case for 625G-->A, together conferring susceptibility to ethylmalonic aciduria."
[5].
"Structural organization of the human short-chain acyl-CoA dehydrogenase gene."
[6].
"Identification of two variant short chain acyl-coenzyme A dehydrogenase alleles, each containing a different point mutation in a patient with short chain acyl-coenzyme A dehydrogenase deficiency."
[7].
"Molecular cloning and nucleotide sequence of complementary DNAs encoding human short chain acyl-coenzyme A dehydrogenase and the study of the molecular basis of human short chain acyl-coenzyme A dehydrogenase deficiency."
[8].
"The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load."
[10].
"Misfolding of short-chain acyl-CoA dehydrogenase leads to mitochondrial fission and oxidative stress."
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