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ACADM (GeneName), Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ProteinName), ACADM_PIG.
Product Name:

Pig ACADM/ Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ELISA Kit

Cat.#:

E10433p

Brand:
EIAab®
Regulatory Status:
Alternative:

MCAD

Detection Method:
ELISA
Specificity:
Natural and recombinant pig Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Cardiovascular
Pig ACADM ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Homotetramer.


Function:
Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).


Subcellular Location:
Mitochondrion matrix


This product has not yet been referenced specifically in any publications.

[1].
"Medium-chain acyl-CoA dehydrogenase (MCAD) mutations identified by MS/MS-based prospective screening of newborns differ from those observed in patients with clinical symptoms: identification and characterization of a new, prevalent mutation that results in mild MCAD deficiency."

[2].
"A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil."

[3].
"A novel tandem mass spectrometry method for rapid confirmation of medium- and very long-chain acyl-CoA dehydrogenase deficiency in newborns."

[4].
"Medium-chain acyl-CoA dehydrogenase deficiency: genotype-biochemical phenotype correlations."

[5].
"Population spectrum of ACADM genotypes correlated to biochemical phenotypes in newborn screening for medium-chain acyl-CoA dehydrogenase deficiency."

[6].
"Newborns with C8-acylcarnitine level over the 90th centile have an increased frequency of the common MCAD 985A>G mutation."

[7].
"Blood acylcarnitine levels in normal newborns and heterozygotes for medium-chain acyl-CoA dehydrogenase deficiency: a relationship between genotype and biochemical phenotype?"

[8].
"Molecular and functional characterisation of mild MCAD deficiency."

[9].
"Evaluation of newborn screening for medium chain acyl-CoA dehydrogenase deficiency in 275 000 babies."

[10].
"Medium chain acyl-CoA dehydrogenase deficiency human genome epidemiology review."
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