ACADM (GeneName), Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ProteinName), ACADM_PIG.
Pig ACADM/ Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ELISA Kit
Natural and recombinant pig Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
MAAMFRRSCR | VLRSLSHFGW | RSQHTKAVPQ | CEPGSGFSFE | LTEQQKEFQA |
TARKFAREEI | IPVAAEYDRT | GEYPVPLLKR | AWELGLMNTH | IPESFGGLGL |
GIIDSCLITE | ELAYGCTGVQ | TAIEANTLGQ | VPLIIGGNYQ | QQKKYLGRMT |
EEPLMCAYCV | TEPGAGSDVA | GIKTKAEKKG | DEYIINGQKM | WITNGGKANW |
YFLLARSDPD | PKAPASKAFT | GFIVEADTPG | VQIGRKEINM | GQRCSDTRGI |
VFEDVRVPKE | NVLTGEGAGF | KIAMGTFDKT | RPPVAAGAVG | LAQRALDEAT |
KYALERKTFG | KLLAEHQGIS | FLLADMAMKV | ELARLSYQRA | AWEIDSGRRN |
TYYASIAKAY | AADIANQLAT | DAVQVFGGNG | FNTEYPVEKL | MRDAKIYQIY |
EGTAQIQRII | IAREHIGRYK | N
This product has not yet been referenced specifically in any publications.
"Medium-chain acyl-CoA dehydrogenase (MCAD) mutations identified by MS/MS-based prospective screening of newborns differ from those observed in patients with clinical symptoms: identification and characterization of a new, prevalent mutation that results in mild MCAD deficiency."
"A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil."
"A novel tandem mass spectrometry method for rapid confirmation of medium- and very long-chain acyl-CoA dehydrogenase deficiency in newborns."
"Medium-chain acyl-CoA dehydrogenase deficiency: genotype-biochemical phenotype correlations."
"Population spectrum of ACADM genotypes correlated to biochemical phenotypes in newborn screening for medium-chain acyl-CoA dehydrogenase deficiency."
"Newborns with C8-acylcarnitine level over the 90th centile have an increased frequency of the common MCAD 985A>G mutation."
"Blood acylcarnitine levels in normal newborns and heterozygotes for medium-chain acyl-CoA dehydrogenase deficiency: a relationship between genotype and biochemical phenotype?"
"Molecular and functional characterisation of mild MCAD deficiency."
"Evaluation of newborn screening for medium chain acyl-CoA dehydrogenase deficiency in 275 000 babies."
"Medium chain acyl-CoA dehydrogenase deficiency human genome epidemiology review."
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