ACADM (GeneName), Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ProteinName), ACADM_PIG.
Product Name:
Pig ACADM/ Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ELISA Kit
Cat.#:
E10433p
Brand:
EIAab®
Regulatory Status:
Alternative:
MCAD
Detection Method:
ELISA
Specificity:
Natural and recombinant pig Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Cardiovascular
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homotetramer.
Function:
Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta-oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
Subcellular Location:
Mitochondrion matrix
Database link
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Medium-chain acyl-CoA dehydrogenase (MCAD) mutations identified by MS/MS-based prospective screening of newborns differ from those observed in patients with clinical symptoms: identification and characterization of a new, prevalent mutation that results in mild MCAD deficiency."
[2].
"A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil."
[3].
"A novel tandem mass spectrometry method for rapid confirmation of medium- and very long-chain acyl-CoA dehydrogenase deficiency in newborns."
[4].
"Medium-chain acyl-CoA dehydrogenase deficiency: genotype-biochemical phenotype correlations."
[5].
"Population spectrum of ACADM genotypes correlated to biochemical phenotypes in newborn screening for medium-chain acyl-CoA dehydrogenase deficiency."
[6].
"Newborns with C8-acylcarnitine level over the 90th centile have an increased frequency of the common MCAD 985A>G mutation."
[7].
"Blood acylcarnitine levels in normal newborns and heterozygotes for medium-chain acyl-CoA dehydrogenase deficiency: a relationship between genotype and biochemical phenotype?"
[9].
"Evaluation of newborn screening for medium chain acyl-CoA dehydrogenase deficiency in 275 000 babies."
[10].
"Medium chain acyl-CoA dehydrogenase deficiency human genome epidemiology review."
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