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Acad8 (GeneName), Isobutyryl-CoA dehydrogenase, mitochondrial (ProteinName), ACAD8_MOUSE.
Product Name:

Mouse Acad8/ Isobutyryl-CoA dehydrogenase, mitochondrial ELISA Kit

Cat.#:

E2437m

Brand:
EIAab®
Regulatory Status:
Alternative:

Acyl-CoA dehydrogenase family member 8, ACAD-8

Detection Method:
ELISA
Assay Type:
Sandwich
Detection Range:
0.312-20ng/mL
Sensitivity:
0.11ng/mL
Specificity:
Natural and recombinant mouse Isobutyryl-CoA dehydrogenase, mitochondrial
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
-
Mouse Acad8 ELISA Kit
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Mouse Acad8 ELISA Kit
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Product Datasheets
Datasheet: Down Datasheet
Instruction: Down Instruction
MSDS: MSDS


General Annotation


Sub Unit:
Homotetramer, formed by a dimer of dimers. Subunit of the large multiprotein complex ARC/DRIP.


Function:
Has very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism.


Subcellular Location:
Mitochondrion


This product has not yet been referenced specifically in any publications.

[1].
"Identification of isobutyryl-CoA dehydrogenase and its deficiency in humans."

[2].
"Structures of isobutyryl-CoA dehydrogenase and enzyme-product complex: comparison with isovaleryl- and short-chain acyl-CoA dehydrogenases."

[3].
"Isolated 2-methylbutyrylglycinuria caused by short/branched-chain acyl-CoA dehydrogenase deficiency: identification of a new enzyme defect, resolution of its molecular basis, and evidence for distinct acyl-CoA dehydrogenases in isoleucine and valine metabolism."

[4].
"Isolation and characterisation of a cDNA encoding the precursor for a novel member of the acyl-CoA dehydrogenase gene family."

[5].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[6].
"Association study of cholesterol-related genes in Alzheimer's disease."

[7].
"Variations in IBD (ACAD8) in children with elevated C4-carnitine detected by tandem mass spectrometry newborn screening."

[8].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"Isobutyryl-CoA dehydrogenase deficiency: isobutyrylglycinuria and ACAD8 gene mutations in two infants."
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