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ACACA (GeneName), Acetyl-CoA carboxylase 1 (ProteinName), ACACA_BOVIN.
Product Name:

Bovine ACACA/ Acetyl-CoA carboxylase 1 ELISA Kit

Cat.#:

E1284b

Brand:
EIAab®
Regulatory Status:
Alternative:

ACC1, ACC-alpha, ACAC, ACCA

Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
78-5000pg/mL
Sensitivity:
29pg/mL
Specificity:
Natural and recombinant bovine Acetyl-CoA carboxylase 1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Assay Procedure
Research Area:
Metabolism
Bovine ACACA ELISA Kit
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Bovine ACACA ELISA Kit
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Product Datasheets
Instruction: Down Instruction
MSDS: MSDS


General Annotation


Sub Unit:
Monomer, homodimer, and homotetramer. Can form filamentous polymers. Interacts in its inactive phosphorylated form with the BRCT domains of BRCA1 which prevents ACACA dephosphorylation and inhibits lipid synthesis. Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity.


Function:
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.


Subcellular Location:
Cytoplasm


This product has not yet been referenced specifically in any publications.

[1].
"Acetyl-CoA carboxylase alpha gene and breast cancer susceptibility."

[2].
"Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels."

[3].
"Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition."

[4].
"BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase."

[5].
"Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes."

[6].
"Acetyl-CoA carboxylase alpha gene and breast cancer susceptibility."

[7].
"Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels."

[8].
"Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition."

[9].
"BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase."

[10].
"Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes."
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