ACACA (GeneName), Acetyl-CoA carboxylase 1 (ProteinName), ACACA_BOVIN.
Product Name:
Bovine ACACA/ Acetyl-CoA carboxylase 1 ELISA Kit
Cat.#:
E1284b
Brand:
EIAab®
Regulatory Status:
Alternative:
ACC1, ACC-alpha, ACAC, ACCA
Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
78-5000pg/mL
Sensitivity:
29pg/mL
Specificity:
Natural and recombinant bovine Acetyl-CoA carboxylase 1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Research Area:
Metabolism
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Monomer, homodimer, and homotetramer. Can form filamentous polymers. Interacts in its inactive phosphorylated form with the BRCT domains of BRCA1 which prevents ACACA dephosphorylation and inhibits lipid synthesis. Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity.
Function:
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Subcellular Location:
Cytoplasm
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[2].
"Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels."
[3].
"Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition."
[4].
"BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase."
[5].
"Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes."
[7].
"Acetyl-coenzyme A carboxylase alpha gene variations may be associated with the direct effects of some antipsychotics on triglyceride levels."
[8].
"Haplotype-based analysis of common variation in the acetyl-coA carboxylase alpha gene and breast cancer risk: a case-control study nested within the European Prospective Investigation into Cancer and Nutrition."
[9].
"BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase."
[10].
"Asymmetric expression of transcripts derived from the shared promoter between the divergently oriented ACACA and TADA2L genes."
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