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ABRA (GeneName), Actin-binding Rho-activating protein (ProteinName), ABRA_HUMAN.
Product Name:

Human ABRA/ Actin-binding Rho-activating protein ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Striated muscle activator of Rho-dependent signaling, STARS

Detection Method:
ELISA
Specificity:
Natural and recombinant human Actin-binding Rho-activating protein
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Human ABRA ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Binds F-actin and ABLIM1, ABLIM2 AND ABLIM3. Interaction with ABLIM2 AND ABLIM3 enhances activity.


Function:
Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.


Subcellular Location:
Cytoplasm Myofibril Sarcomere Cytoplasm Cytoskeleton Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines.


This product has not yet been referenced specifically in any publications.

[1].
"STARS, a striated muscle activator of Rho signaling and serum response factor-dependent transcription."

[2].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[3].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[4].
"Striated muscle activator of Rho signalling (STARS) is reduced in ageing human skeletal muscle and targeted by miR-628-5p."

[5].
"Identification of striated muscle activator of Rho signaling (STARS) as a novel calmodulin target by a newly developed genome-wide screen."

[6].
"Effect of resistance exercise contraction mode and protein supplementation on members of the STARS signalling pathway."

[7].
"Genome-wide association scan of dental caries in the permanent dentition."

[8].
"Striated muscle activator of Rho signalling (STARS) is a PGC-1α/oestrogen-related receptor-α target gene and is upregulated in human skeletal muscle after endurance exercise."

[9].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."

[10].
"Regulation of STARS and its downstream targets suggest a novel pathway involved in human skeletal muscle hypertrophy and atrophy."
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