Abhd6 (GeneName), Monoacylglycerol lipase ABHD6 (ProteinName), ABHD6_RAT.
Product Name:
Rat Abhd6/ Monoacylglycerol lipase ABHD6 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 6
Detection Method:
ELISA
Specificity:
Natural and recombinant rat Monoacylglycerol lipase ABHD6
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
N/A
Function:
Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. May also have a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Mitochondrion
Database link
UniGene:
SMR:
STRING:
KEGG:
Pfam:
Uniprot:
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)."
[2].
"Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors."
[3].
"An unannotated alpha/beta hydrolase superfamily member, ABHD6 differentially expressed among cancer cell lines."
[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[6].
"Architecture of the human interactome defines protein communities and disease networks."
[8].
"α/β-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes."
[9].
"α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors."
[10].
"PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6."
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