ABHD4 (GeneName), (Lyso)-N-acylphosphatidylethanolamine lipase (ProteinName), ABHD4_HUMAN.
Product Name:
Human ABHD4/ (Lyso)-N-acylphosphatidylethanolamine lipase ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Alpha/beta hydrolase domain-containing protein 4, Abhydrolase domain-containing protein 4, Alpha/beta-hydrolase 4
Detection Method:
ELISA
Specificity:
Natural and recombinant human (Lyso)-N-acylphosphatidylethanolamine lipase
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
N/A
Function:
Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.
Subcellular Location:
N/A
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[2].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[3].
"A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance."
[4].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
[5].
"A directed protein interaction network for investigating intracellular signal transduction."
[7].
"A shifted repertoire of endocannabinoid genes in the zebrafish (Danio rerio)."
[8].
"Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway."
[10].
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
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