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ABHD4 (GeneName), (Lyso)-N-acylphosphatidylethanolamine lipase (ProteinName), ABHD4_HUMAN.
Product Name:

Human ABHD4/ (Lyso)-N-acylphosphatidylethanolamine lipase ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

Alpha/beta hydrolase domain-containing protein 4, Abhydrolase domain-containing protein 4, Alpha/beta-hydrolase 4

Detection Method:
ELISA
Specificity:
Natural and recombinant human (Lyso)-N-acylphosphatidylethanolamine lipase
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Human ABHD4 ELISA Kit
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Human ABHD4 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
N/A


Function:
Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.


Subcellular Location:
N/A


This product has not yet been referenced specifically in any publications.

[1].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[2].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[3].
"A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance."

[4].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."

[5].
"A directed protein interaction network for investigating intracellular signal transduction."

[6].
"Toward a confocal subcellular atlas of the human proteome."

[7].
"A shifted repertoire of endocannabinoid genes in the zebrafish (Danio rerio)."

[8].
"Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway."

[9].
"The DNA sequence and analysis of human chromosome 14."

[10].
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."
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