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ABHD2 (基因名), Monoacylglycerol lipase ABHD2 (蛋白名), ABHD2_HUMAN.
产品名称:

Human ABHD2/ Monoacylglycerol lipase ABHD2 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 2, Acetylesterase, Lung alpha/beta hydrolase 2, Progesterone-sensitive lipase, Protein PHPS1-2, LABH2

检测方法:
ELISA
特异性:
Natural and recombinant human Monoacylglycerol lipase ABHD2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human ABHD2 ELISA Kit
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Human ABHD2 ELISA Kit
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亚单元:
N/A


功能:
Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane (PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA) (PubMed:26989199). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester (PubMed:27247428). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation (PubMed:26989199). May also play a role in smooth muscle cells migration (By similarity).


亚细胞位置:
Cell projection Cilium Flagellum membrane Single-pass type II membrane protein Cell membrane Single-pass type II membrane protein


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