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Apobec2 (GeneName), C->U-editing enzyme APOBEC-2 (ProteinName), ABEC2_MOUSE.
Product Name:

Mouse Apobec2/ C->U-editing enzyme APOBEC-2 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

mRNA(cytosine(6666)) deaminase 2

Detection Method:
ELISA
Specificity:
Natural and recombinant mouse C->U-editing enzyme APOBEC-2
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Mouse Apobec2 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Homotetramer.


Function:
Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.


Subcellular Location:
N/A


This product has not yet been referenced specifically in any publications.

[1].
"APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family."

[2].
"The APOBEC-2 crystal structure and functional implications for the deaminase AID."

[3].
"Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain."

[4].
"Gender differences in genetic risk profiles for cardiovascular disease."

[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[6].
"The DNA sequence and analysis of human chromosome 6."

[7].
"ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing."

[8].
"Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis."

[9].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."

[10].
"Microarray analysis of tonsils in immunoglobulin A nephropathy patients."
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