APOBEC2 (GeneName), C->U-editing enzyme APOBEC-2 (ProteinName), ABEC2_HUMAN.
Product Name:
Human APOBEC2/ C->U-editing enzyme APOBEC-2 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
mRNA(cytosine(6666)) deaminase 2
Detection Method:
ELISA
Specificity:
Natural and recombinant human C->U-editing enzyme APOBEC-2
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homotetramer.
Function:
Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Subcellular Location:
N/A
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family."
[2].
"The APOBEC-2 crystal structure and functional implications for the deaminase AID."
[3].
"Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain."
[5].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
[7].
"ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing."
[8].
"Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis."
[9].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
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