APOBEC2 (GeneName), Probable C->U-editing enzyme APOBEC-2 (ProteinName), ABEC2_BOVIN.
Bovine APOBEC2/ Probable C->U-editing enzyme APOBEC-2 ELISA Kit
mRNA(cytosine(6666)) deaminase 2
Natural and recombinant bovine Probable C->U-editing enzyme APOBEC-2
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
MAQKEEAAAA | AEPASQNGEE | VENLEDPEKL | KELIELPPFE | IVTGERLPAH |
YFKFQFRNVE | YSSGRNKTFL | CYVVEAQSKG | GQVQASRGYL | EDEHATNHAE |
EAFFNSIMPT | FDPALRYMVT | WYVSSSPCAA | CADRIVKTLN | KTKNLRLLIL |
VGRLFMWEEP | EIQAALRKLK | EAGCRLRIMK | PQDFEYIWQN | FVEQEEGESK |
AFEPWEDIQE | NFLYYEEKLA | DILK
This product has not yet been referenced specifically in any publications.
"APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family."
"The APOBEC-2 crystal structure and functional implications for the deaminase AID."
"Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain."
"Gender differences in genetic risk profiles for cardiovascular disease."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
"The DNA sequence and analysis of human chromosome 6."
"ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing."
"Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis."
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."
"Microarray analysis of tonsils in immunoglobulin A nephropathy patients."
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