Apobec1 (GeneName), C->U-editing enzyme APOBEC-1 (ProteinName), ABEC1_RAT.
Product Name:
Rat Apobec1/ C->U-editing enzyme APOBEC-1 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Apolipoprotein B mRNA-editing enzyme 1, mRNA(cytosine(6666)) deaminase 1
Detection Method:
ELISA
Specificity:
Natural and recombinant rat C->U-editing enzyme APOBEC-1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homodimer. Part of the apolipoprotein B mRNA editing complex with A1CF. Interacts with SYNCRIP. Interacts with HNRPAB.
Function:
Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation.
Subcellular Location:
Cytoplasm
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease."
[2].
"C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme."
[4].
"Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein."
[5].
"Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor."
[6].
"The expression of apoB mRNA editing factors is not the sole determinant for the induction of editing in differentiating Caco-2 cells."
[7].
"Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus."
[9].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
[10].
"Simultaneous expression of apolipoprotein B mRNA editing enzyme and scavenger receptor BI mediated by a therapeutic gene expression system."
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