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ABHD12 (基因名), Lysophosphatidylserine lipase ABHD12 (蛋白名), ABD12_HUMAN.
产品名称:

Human ABHD12/ Lysophosphatidylserine lipase ABHD12 ELISA Kit

货号:

E6236h

商标:
EIAab®
监管等级:
别名:

2-arachidonoylglycerol hydrolase ABHD12, Abhydrolase domain-containing protein 12, Monoacylglycerol lipase ABHD12, Oxidized phosphatidylserine lipase ABHD12, hABHD12, C20orf22

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.312-20ng/mL
灵敏度:
0.168ng/mL
特异性:
Natural and recombinant human Lysophosphatidylserine lipase ABHD12
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Human ABHD12 ELISA Kit
规格 & 价格: cart
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Human ABHD12 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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通用注释


亚单元:
N/A


功能:
Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (PubMed:25290914, PubMed:30237167, PubMed:30420694, PubMed:30720278, PubMed:30643283). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal (PubMed:30643283). Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways (PubMed:22969151, PubMed:24027063). Has a strong preference for very-long-chain lipid substrates; substrate specificity is likely due to improved catalysis and not improved substrate binding (PubMed:30237167).


亚细胞位置:
Endoplasmic reticulum membrane Single-pass membrane protein


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