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首页  >  酶联免疫试剂盒  >  Chicken ABHD12 ELISA Kit
ABHD12 (基因名), Lysophosphatidylserine lipase ABHD12 (蛋白名), ABD12_CHICK.
产品名称:

Chicken ABHD12/ Lysophosphatidylserine lipase ABHD12 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

Abhydrolase domain-containing protein 12, RCJMB04_24m17, 2-arachidonoylglycerol hydrolase ABHD12, Monoacylglycerol lipase ABHD12, Oxidized phosphatidylserine lipase ABHD12

检测方法:
ELISA
特异性:
Natural and recombinant chicken Lysophosphatidylserine lipase ABHD12
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Chicken ABHD12 ELISA Kit
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产品说明书


通用注释


亚单元:
N/A


功能:
Lysophosphatidylserine (LPS) lipase that mediates the hydrolysis of lysophosphatidylserine, a class of signaling lipids that regulates immunological and neurological processes (By similarity). Represents a major lysophosphatidylserine lipase in the brain, thereby playing a key role in the central nervous system (By similarity). Also able to hydrolyze oxidized phosphatidylserine; oxidized phosphatidylserine is produced in response to severe inflammatory stress and constitutes a proapoptotic 'eat me' signal. Also has monoacylglycerol (MAG) lipase activity: hydrolyzes 2-arachidonoylglycerol (2-AG), thereby acting as a regulator of endocannabinoid signaling pathways. Has a strong preference for very-long-chain lipid substrates; substrate specificity is likely due to improved catalysis and not improved substrate binding (By similarity).


亚细胞位置:
Endoplasmic reticulum membrane Single-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)."

[2].
"Biochemical and pharmacological characterization of the human lymphocyte antigen B-associated transcript 5 (BAT5/ABHD16A)."

[3].
"Two novel mutations in ABHD12: expansion of the mutation spectrum in PHARC and assessment of their functional effects."

[4].
"Targeted next-generation sequencing identifies a homozygous nonsense mutation in ABHD12, the gene underlying PHARC, in a family clinically diagnosed with Usher syndrome type 3."

[5].
"Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma."
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