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Abcf1 (GeneName), ATP-binding cassette sub-family F member 1 (ProteinName), ABCF1_RAT.
Product Name:

Rat Abcf1/ ATP-binding cassette sub-family F member 1 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

ATP-binding cassette 50, Abc50

Detection Method:
ELISA
Specificity:
Natural and recombinant rat ATP-binding cassette sub-family F member 1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
Rat Abcf1 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
Interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Associates (via both ABC transporter domains) with the ribosomes.


Function:
Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis.


Subcellular Location:
Cytoplasm Nucleus Nucleoplasm Nucleus envelope


This product has not yet been referenced specifically in any publications.

[1].
"The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2."

[2].
"ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes."

[3].
"Identification of independent risk loci for Graves' disease within the MHC in the Japanese population."

[4].
"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."

[5].
"ABC50 promotes translation initiation in mammalian cells."

[6].
"High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions."

[7].
"HLA-E gene polymorphism associates with ankylosing spondylitis in Sardinia."

[8].
"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."

[9].
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."

[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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