Abcf1 (GeneName), ATP-binding cassette sub-family F member 1 (ProteinName), ABCF1_RAT.
Rat Abcf1/ ATP-binding cassette sub-family F member 1 ELISA Kit
ATP-binding cassette 50, Abc50
Natural and recombinant rat ATP-binding cassette sub-family F member 1
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Associates (via both ABC transporter domains) with the ribosomes.
Required for efficient Cap- and IRES-mediated mRNA translation initiation. Not involved in the ribosome biogenesis.
Cytoplasm Nucleus Nucleoplasm Nucleus envelope
MPKGPKQQPP | EPEWIGDGEG | TSPADKVVKK | GKKDKKTKKT | FFEELAVEDK |
QAGEEEKLQK | EKEQQQQQQQ | QKKKRDTRKG | RRKKDVDDDD | DGDERVLMER |
LKQLSVPASD | EEDEVPVPVP | RGRKKAKGGN | VFEALIQDES | EEEKEEEEEK |
PVLKPAKPEK | NRINKAVAEE | PPGLRNKKGK | EEKSKGKAKN | KPSATDSEGE |
DDEDMTKEKE | PPRPGKDKDK | KGAEQGSEEE | KEEKEGEVKA | NDPYAHLSKK |
EKKKLKKQMD | YERQVESLKA | ANAAENDFSV | SQAEVSSRQA | MLENASDIKL |
EKFSISAHGK | ELFVNADLYI | VAGRRYGLVG | PNGKGKTTLL | KHIANRALSI |
PPNIDVLLCE | QEVVADETPA | VQAVLRADTK | RLRLLEEEKR | LQGQLEQGDD |
TAAEKLEKVY | EELRATGAAA | AEAKARRILA | GLGFDPEMQN | RPTQKFSGGW |
RMRVSLARAL | FMEPTLLMLD | EPTNHLDLNA | VIWLNNYLQG | WRKTLLIVSH |
DQGFLDDVCT | DIIHLDTQRL | HYYRGNYMTF | KKMYQQKQKE | LLKQYEKQEK |
KLKELKAGGK | STKQAEKQTK | EVLTRKQQKC | RRKNQDEESQ | DPPELLKRPR |
EYTVRFTFPD | PPPLSPPVLG | LHGVTFGYEG | QKPLFKNLDF | GIDMDSRICI |
VGPNGVGKST | LLLLLTGKLT | PTNGEMRKNH | RLKIGFFNQQ | YAEQLHMEET |
PTEYLQRGFN | LPYQDARKCL | GRFGLESHAH | TIQICKLSGG | QKARVVFAEL |
ACREPDVLIL | DEPTNNLDIE | SIDALGEAIN | EYKGAVIVVS | HDARLITETN |
CQLWVVEEQS | VSQIDGDFDD | YKREVLEALG | EVMVNRPRD
This product has not yet been referenced specifically in any publications.
"The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2."
"ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes."
"Identification of independent risk loci for Graves' disease within the MHC in the Japanese population."
"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."
"ABC50 promotes translation initiation in mammalian cells."
"High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions."
"HLA-E gene polymorphism associates with ankylosing spondylitis in Sardinia."
"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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