ABCF1 (GeneName), ATP-binding cassette sub-family F member 1 (ProteinName), ABCF1_HUMAN.
Human ABCF1/ ATP-binding cassette sub-family F member 1 ELISA Kit
ATP-binding cassette 50, TNF-alpha-stimulated ABC protein, ABC50
Natural and recombinant human ATP-binding cassette sub-family F member 1
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Isoform 2 interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Isoform 2 associates (via both ABC transporter domains) with the ribosomes.
Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
Isoform 2 Cytoplasm Nucleus Nucleoplasm Nucleus envelope
MPKAPKQQPP | EPEWIGDGES | TSPSDKVVKK | GKKDKKIKKT | FFEELAVEDK |
QAGEEEKVLK | EKEQQQQQQQ | QQQKKKRDTR | KGRRKKDVDD | DGEEKELMER |
LKKLSVPTSD | EEDEVPAPKP | RGGKKTKGGN | VFAALIQDQS | EEEEEEEKHP |
PKPAKPEKNR | INKAVSEEQQ | PALKGKKGKE | EKSKGKAKPQ | NKFAALDNEE |
EDKEEEIIKE | KEPPKQGKEK | AKKAEQGSEE | EGEGEEEEEE | GGESKADDPY |
AHLSKKEKKK | LKKQMEYERQ | VASLKAANAA | ENDFSVSQAE | MSSRQAMLEN |
ASDIKLEKFS | ISAHGKELFV | NADLYIVAGR | RYGLVGPNGK | GKTTLLKHIA |
NRALSIPPNI | DVLLCEQEVV | ADETPAVQAV | LRADTKRLKL | LEEERRLQGQ |
LEQGDDTAAE | RLEKVYEELR | ATGAAAAEAK | ARRILAGLGF | DPEMQNRPTQ |
KFSGGWRMRV | SLARALFMEP | TLLMLDEPTN | HLDLNAVIWL | NNYLQGWRKT |
LLIVSHDQGF | LDDVCTDIIH | LDAQRLHYYR | GNYMTFKKMY | QQKQKELLKQ |
YEKQEKKLKE | LKAGGKSTKQ | AEKQTKEALT | RKQQKCRRKN | QDEESQEAPE |
LLKRPKEYTV | RFTFPDPPPL | SPPVLGLHGV | TFGYQGQKPL | FKNLDFGIDM |
DSRICIVGPN | GVGKSTLLLL | LTGKLTPTHG | EMRKNHRLKI | GFFNQQYAEQ |
LRMEETPTEY | LQRGFNLPYQ | DARKCLGRFG | LESHAHTIQI | CKLSGGQKAR |
VVFAELACRE | PDVLILDEPT | NNLDIESIDA | LGEAINEYKG | AVIVVSHDAR |
LITETNCQLW | VVEEQSVSQI | DGDFEDYKRE | VLEALGEVMV | SRPRE
This product has not yet been referenced specifically in any publications.
"The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2."
"ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes."
"Identification of independent risk loci for Graves' disease within the MHC in the Japanese population."
"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."
"ABC50 promotes translation initiation in mammalian cells."
"High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions."
"HLA-E gene polymorphism associates with ankylosing spondylitis in Sardinia."
"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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