ABCF1 (GeneName), ATP-binding cassette sub-family F member 1 (ProteinName), ABCF1_HUMAN.
Product Name:
Human ABCF1/ ATP-binding cassette sub-family F member 1 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
ATP-binding cassette 50, TNF-alpha-stimulated ABC protein, ABC50
Detection Method:
ELISA
Specificity:
Natural and recombinant human ATP-binding cassette sub-family F member 1
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Isoform 2 interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Isoform 2 associates (via both ABC transporter domains) with the ribosomes.
Function:
Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
Subcellular Location:
Isoform 2
Cytoplasm
Nucleus
Nucleoplasm
Nucleus envelope
This product has not yet been referenced specifically in any publications.
[1].
"The N-terminal region of ABC50 interacts with eukaryotic initiation factor eIF2 and is a target for regulatory phosphorylation by CK2."
[2].
"ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes."
[3].
"Identification of independent risk loci for Graves' disease within the MHC in the Japanese population."
[4].
"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."
[6].
"High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions."
[8].
"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
[9].
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
[10].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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