Abcd3 (GeneName), ATP-binding cassette sub-family D member 3 (ProteinName), ABCD3_RAT.
Product Name:
Rat Abcd3/ ATP-binding cassette sub-family D member 3 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
70 kDa peroxisomal membrane protein, PMP70, Pmp70, Pxmp1
Detection Method:
ELISA
Specificity:
Natural and recombinant rat ATP-binding cassette sub-family D member 3
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homodimer or heterodimer (Potential). Interacts with PEX19.
Function:
Probable transporter involved in the transport of branched-chain fatty acids and C27 bile acids into the peroxisome; the latter function is a crucial step in bile acid biosynthesis. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.
Subcellular Location:
Peroxisome membrane
Multi-pass membrane protein
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome."
[2].
"Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP binding cassette transporters."
[3].
"Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p."
[4].
"Genomic organization of the 70-kDa peroxisomal membrane protein gene (PXMP1)."
[5].
"Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a member of ATP-binding cassette transporters."
[6].
"A novel bile acid biosynthesis defect due to a deficiency of peroxisomal ABCD3."
[7].
"Multiple organelle-targeting signals in the N-terminal portion of peroxisomal membrane protein PMP70."
[8].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."
[9].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."
[10].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."
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