Home > ELISA Kit > Human ABCD2 ELISA Kit

ABCD2 (GeneName), ATP-binding cassette sub-family D member 2 (ProteinName), ABCD2_HUMAN.

Product Name:

Human ABCD2/ ATP-binding cassette sub-family D member 2 ELISA Kit

Cat.#:

Brand:

EIAab^®

Regulatory Status:

RUO

Alternative:

Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein, hALDR, ALD1, ALDL1, ALDR, ALDRP

Detection Method:

ELISA

Specificity:

Natural and recombinant human ATP-binding cassette sub-family D member 2

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Research Area:

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Human ABCD2 ELISA Kit

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Product Datasheets

Data
Citations
Publication
Sequence / 3D
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General Annotation

Sub Unit:

Can form heterodimers with ABCD1/ALD and ABCD3/PMP70. Dimerization is necessary to form an active transporter. Interacts with PEX19.

Function:

Probable transporter.

Subcellular Location:

Peroxisome membrane Multi-pass membrane protein

Database link

UniGene:

Hs.117852

STRING:

9606.ENSP00000310688

KEGG:

hsa:225

MIM:

601081

Pfam:

PF06472

Uniprot:

Q9UBJ2

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Sequence length:

740

Sequence:

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740:

QKLESQLAGI | PKMQQRLNEL | CKILGEDSVL | KTIKNEDETS |

3D Structure:

Predicted Epitope:

Valid Sequence:

This product has not yet been referenced specifically in any publications.

[1].

"A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern."

(PMID: 8577752)

[2].

"Human adrenoleukodystrophy protein and related peroxisomal ABC transporters interact with the peroxisomal assembly protein PEX19p."

(PMID: 10777694)

[3].

"Full length cDNA cloning, promoter sequence, and genomic organization of the human adrenoleukodystrophy related (ALDR) gene functionally redundant to the gene responsible for X-linked adrenoleukodystrophy."

(PMID: 10329405)

[4].

"cDNA cloning and mRNA expression of the human adrenoleukodystrophy related protein (ALDRP), a peroxisomal ABC transporter."

(PMID: 9345306)

[5].

"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

(PMID: 20877624)

[6].

"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."

(PMID: 19343046)

[7].

"Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations."

(PMID: 18660489)

[8].

"X-linked adrenoleukodystrophy phenotype is independent of ABCD2 genotype."

(PMID: 18834860)

[9].

"Effect of testosterone metabolites on ABC half-transporter relative gene expression in X-linked adrenoleukodystrophy."

(PMID: 17602313)

[10].

"Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation."