ABCC9 (GeneName), ATP-binding cassette sub-family C member 9 (ProteinName), ABCC9_HUMAN.
Product Name:
Human ABCC9/ ATP-binding cassette sub-family C member 9 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Sulfonylurea receptor 2, SUR2
Detection Method:
ELISA
Specificity:
Natural and recombinant human ATP-binding cassette sub-family C member 9
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Interacts with KCNJ11.
Function:
Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Subcellular Location:
Membrane
Multi-pass membrane protein
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Genes controlling postural changes in blood pressure: comprehensive association analysis of ATP-sensitive potassium channel genes KCNJ8 and ABCC9."
[2].
"ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating."
[4].
"Differential mechanisms of Cantú syndrome-associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel."
[5].
"A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila."
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