Abcc8 (GeneName), ATP-binding cassette sub-family C member 8 (ProteinName), ABCC8_RAT.
Product Name:
Rat Abcc8/ ATP-binding cassette sub-family C member 8 ELISA Kit
Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:
Sulfonylurea receptor 1, Sur, Sur1
Detection Method:
ELISA
Specificity:
Natural and recombinant rat ATP-binding cassette sub-family C member 8
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Interacts with KCNJ11.
Function:
Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Database link
This product has not yet been referenced specifically in any publications.
[1].
"Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians."
[2].
"Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations."
[3].
"Metabolic control in type 2 diabetes is associated with sulfonylurea receptor-1 (SUR-1) but not with KCNJ11 polymorphisms."
[4].
"Effect of genetic variants in KCNJ11, ABCC8, PPARG and HNF4A loci on the susceptibility of type 2 diabetes in Chinese Han population."
[5].
"The spectrum of ABCC8 mutations in Norwegian patients with congenital hyperinsulinism of infancy."
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