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首页  >  酶联免疫试剂盒  >  Human ABCB11 ELISA Kit
ABCB11 (基因名), Bile salt export pump (蛋白名), ABCBB_HUMAN.
产品名称:

Human ABCB11/ Bile salt export pump ELISA Kit
胆盐出口泵

货号:

E10415h

商标:
EIAab®
监管等级:
别名:

ATP-binding cassette sub-family B member 11, BSEP

检测方法:
ELISA
实验类型:
Sandwich
检测范围:
78-5000pg/ml
灵敏度:
40pg/mL
特异性:
Natural and recombinant human Bile salt export pump
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
Cardiovascular
Human ABCB11 ELISA Kit
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产品说明书
数据表: 下载说明书
说明书: 下载说明书
MSDS: MSDS


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤6.9%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤9.4%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

101

95-107

Plasma

103

97-109

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

97-107%

101-113%

97-107%

89-97%

EDTA plasma(n=5)

102-112%

103-113%

96-106%

94-104%

heparin plasma(n=5)

101-111%

 

111-120%

83-92%

109-120%

 

通用注释


亚单元:
Interacts with HAX1.


功能:
Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.


亚细胞位置:
Membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury."

[2].
"Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy."

[3].
"A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis."

[4].
"Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability."

[5].
"Common variants of ABCB4 and ABCB11 and plasma lipid levels: a study in sib pairs with gallstones, and controls."

[6].
"Genetic variability, haplotype structures, and ethnic diversity of hepatic transporters MDR3 (ABCB4) and bile salt export pump (ABCB11)."

[7].
"Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis."

[8].
"BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis."

[9].
"FIC1 and BSEP defects in Taiwanese patients with chronic intrahepatic cholestasis with low gamma-glutamyltranspeptidase levels."

[10].
"Diagnosis of ABCB11 gene mutations in children with intrahepatic cholestasis using high resolution melting analysis and direct sequencing."
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