Abcb9 (GeneName), ATP-binding cassette sub-family B member 9 (ProteinName), ABCB9_RAT.
Product Name:
Rat Abcb9/ ATP-binding cassette sub-family B member 9 ELISA Kit
Cat.#:
E1181r
Brand:
EIAab®
Regulatory Status:
Alternative:
ATP-binding cassette transporter 9, ABC transporter 9 protein, TAP-like protein, TAPL
Detection Method:
ELISA
Assay Type:
Competitive
Detection Range:
0.156-10ng/mL
Sensitivity:
0.063ng/mL
Specificity:
Natural and recombinant rat ATP-binding cassette sub-family B member 9
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Assay Procedure:
Research Area:
-
- Data
- Citations
- Publication
- Sequence / 3D
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General Annotation
Sub Unit:
Homodimer.
Function:
ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored.
Subcellular Location:
Lysosome membrane
Multi-pass membrane protein
May be located in membrane rafts.
Database link
Valid Sequence:
This product has not yet been referenced specifically in any publications.
[1].
"Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells."
[2].
"Peptide specificity and lipid activation of the lysosomal transport complex ABCB9 (TAPL)."
[4].
"Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9)."
[5].
"Membrane localization of transporter associated with antigen processing (TAP)-like (ABCB9) visualized in vivo with a fluorescence protein-fusion technique."
[6].
"Gene organization of human transporter associated with antigen processing-like (TAPL, ABCB9): analysis of alternative splicing variants and promoter activity."
[7].
"Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes."
[8].
"Transporter associated with antigen processing-like (ABCB9) stably expressed in Chinese hamster ovary-K1 cells is sorted to the microdomains of lysosomal membranes."
[9].
"Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women."
[10].
"Tuning the cellular trafficking of the lysosomal peptide transporter TAPL by its N-terminal domain."
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