Home > ELISA Kit > Human ABCB9 ELISA Kit

ABCB9 (GeneName), ATP-binding cassette sub-family B member 9 (ProteinName), ABCB9_HUMAN.

Product Name:

Human ABCB9/ ATP-binding cassette sub-family B member 9 ELISA Kit

Cat.#:

E1181h

Brand:

EIAab^®

Regulatory Status:

RUO

Alternative:

ATP-binding cassette transporter 9, ABC transporter 9 protein, TAP-like protein, TAPL, KIAA1520

Detection Method:

ELISA

Assay Type:

Sandwich

Detection Range:

78-5000pg/mL

Sensitivity:

40.6pg/mL

Specificity:

Natural and recombinant human ATP-binding cassette sub-family B member 9

Sample Type:

Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids

Sample Data:

Assay Procedure:

Research Area:

Size & Price: Sign In.

Attention

Human ABCB9 ELISA Kit

Email *

Message *

Please Sign In.

Product Datasheets

Instruction:

MSDS:

Data
Citations
Publication
Sequence / 3D
Feedback Wall (0)

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤5.0%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤6.3%

Recovery

Recovery was determined by spiking various levels of ATP-binding cassette sub-family B member 9 into serum and plasma.

Sample Type	Average(%)	Recovery Range(%)
Serum	95	89-101
Plasma	97	91-103

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ATP-binding cassette sub-family B member 9 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	110-119%	93-102%	92-101%	102-113%
EDTA plasma(n=5)	105-116%	106-116%	108-118%	108-118%
heparin plasma(n=5)	86-97%	94-104%	94-104%	107-119%

General Annotation

Sub Unit:

Homodimer.

Function:

ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored.

Subcellular Location:

Lysosome membrane Multi-pass membrane protein May be located in membrane rafts.

Database link

UniGene:

Hs.511951

SMR:

Q9NP78

STRING:

9606.ENSP00000280560

KEGG:

hsa:23457

MIM:

605453

Pfam:

PF00664

Uniprot:

Q9NP78

Related Product

Mouse Abcb9 ELISA Kit

Sequence length:

766

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

766:

FTAGHNEPVA | NGSHKA

3D Structure:

Predicted Epitope:

Valid Sequence:

This product has not yet been referenced specifically in any publications.

[1].

"Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells."

(PMID: 18175933)

[2].

"Peptide specificity and lipid activation of the lysosomal transport complex ABCB9 (TAPL)."

(PMID: 18434309)

[3].

"Functional dissection of transmembrane domains of human TAP-like (ABCB9)."

(PMID: 18952056)

[4].

"Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9)."

(PMID: 15863492)

[5].

"Membrane localization of transporter associated with antigen processing (TAP)-like (ABCB9) visualized in vivo with a fluorescence protein-fusion technique."

(PMID: 15577206)

[6].

"Gene organization of human transporter associated with antigen processing-like (TAPL, ABCB9): analysis of alternative splicing variants and promoter activity."

(PMID: 13679046)

[7].

"Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes."

(PMID: 10748049)

[8].

"Transporter associated with antigen processing-like (ABCB9) stably expressed in Chinese hamster ovary-K1 cells is sorted to the microdomains of lysosomal membranes."

(PMID: 21212514)

[9].

"Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women."

(PMID: 21507922)

[10].

"Tuning the cellular trafficking of the lysosomal peptide transporter TAPL by its N-terminal domain."

(PMID: 20377823)

Feedback Wall

Displaying result : 0

All customer

Default sort

Newest first