Abcb7 (GeneName), ATP-binding cassette sub-family B member 7, mitochondrial (ProteinName), ABCB7_MOUSE.
Mouse Abcb7/ ATP-binding cassette sub-family B member 7, mitochondrial ELISA Kit
ATP-binding cassette transporter 7, ABC transporter 7 protein, Abc7
Natural and recombinant mouse ATP-binding cassette sub-family B member 7, mitochondrial
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Homodimer or heterodimer.
Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Mitochondrion inner membrane Multi-pass membrane protein
MALLAIHSWR | WAAAAVAFEK | HKHSAVLTRA | LVSMCGSGPR | WSSSQRGASG |
SARLSQTTES | LRNTTQQRWG | KDNSRQLLDA | TKALQTWPLI | EKRTCWHGHA |
GGGLHTDPKE | GLKDVDTRKI | IKAMLSYVWP | EDRPDLRARV | AISLGFLGGA |
KAMNIVVPFM | FKYAVDSLNQ | MSGNMLNLSD | APNTVATMAT | AVLIGYGVSR |
AGAAFFNEVR | NAVFGKVAQN | SIRRIAKNVF | LHLHNLDLGF | HLSRQTGALS |
KAIDRGTRGI | SFVLSALVFN | LLPIVFEMML | VSSVLYYKCG | AQFALVTLGT |
LGAYTAFTVA | VTRWRTRFRI | EMNKADNDAG | NAAIDSLLNY | ETVKYFNNEK |
YEAQRYDGFL | KTYETASLKS | TSTLAMLNFG | QNAIFSVGLT | AIMVLASQGI |
VAGALTVGDL | VMVNGLLFQL | SLPLNFLGTV | YRETRQALID | MNTLFTLLKV |
DTRIKDKVMA | PPLQITPQTA | TVAFDNVHFE | YIEGQKVLNG | VSFEVPAGKK |
VAIVGGSGSG | KSTIVRLLFR | FYEPQKGSIY | LAGQNLQDVS | LESLRRAVGV |
VPQDAVLFHN | TIYYNLLYGN | INASPEEVYA | VAKLAGLHDA | ILRMPHGYDT |
QVGERGLKLS | GGEKQRVAIA | RAILKNPPVI | LYDEATSSLD | SITEETILGA |
MRDVVKHRTS | IFIAHRLSTV | VDADEIIVLS | QGKVAERGTH | YGLLANSSSI |
YSEMWHTQSN | RVQNQDSLGW | DAKKESLSKE | EERKKLQEEI | VNSVKGCGNC |
This product has not yet been referenced specifically in any publications.
"X-linked cerebellar ataxia and sideroblastic anaemia associated with a missense mutation in the ABC7 gene predicting V411L."
"Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation."
"Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A)."
"Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human."
"X-linked sideroblastic anemia and ataxia: a new family with identification of a fourth ABCB7 gene mutation."
"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."
"The role of the iron transporter ABCB7 in refractory anemia with ring sideroblasts."
"The DNA sequence of the human X chromosome."
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
"Involvement of ABC7 in the biosynthesis of heme in erythroid cells: interaction of ABC7 with ferrochelatase."
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