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首页  >  酶联免疫试剂盒  >  Rat Abca7 ELISA Kit
Abca7 (基因名), ATP-binding cassette sub-family A member 7 (蛋白名), ABCA7_RAT.
产品名称:

Rat Abca7/ ATP-binding cassette sub-family A member 7 ELISA Kit
ATP结合盒亚家族A7

货号:

E15004r

商标:
EIAab®
监管等级:
检测方法:
ELISA
实验类型:
Sandwich
检测范围:
0.156-10ng/mL
灵敏度:
0.061ng/mL
特异性:
Natural and recombinant rat ATP-binding cassette sub-family A member 7
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
实验步骤:
实验步骤
研究领域:
-
Rat Abca7 ELISA Kit
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产品说明书
说明书: 下载说明书
MSDS: MSDS


精密度
批内差:已知浓度的3个样本在一个板子内重复检测20次,以评估批内精密度。
批内 CV: ≤3.8%
批间差:已知浓度的3个样本在不同的板子上重复测定5次,以评估测定批间精密度。
批间 CV: ≤7.5%
回收率
回收率:低、中和高浓度的分析物被掺入到血清或者血浆样本中,进行回收实验测定。

Sample Type

Average(%)

Recovery Range(%)

Serum

84

80-90

Plasma

86

80-92

 

 

 

 

线性
线性:给定样本通过梯度稀释,每次稀释的测量值与理论值的比值。

Sample

1:2

1:4

1:8

1:16

serum(n=5)

100-109%

111-120%

106-116%

105-115%

EDTA plasma(n=5)

101-112%

90-100%

90-100%

99-109%

heparin plasma(n=5)

106-116%

 

105-115%

100-110%

103-113%

 

通用注释


亚单元:
N/A


功能:
Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.


亚细胞位置:
Cell membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein Endosome membrane Multi-pass membrane protein Localizes to cell membrane ruffles and phagocytic cups of macrophages stimulated with C1q or apoptotic cells. Localizes to the cytoplasm of resting macrophages, probably in Golgi and endosomes. Localizes to the apical brush border of cells in the proximal tubules of kidney.


该产品尚未在任何出版物中被引用。

[1].
"Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein."

[2].
"Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7)."

[3].
"Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease."

[4].
"Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study."

[5].
"Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease."

[6].
"Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease."

[7].
"Genetic susceptibility to distinct bladder cancer subphenotypes."

[8].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[9].
"Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease."

[10].
"Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China."
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