本公司产品仅供科研使用,不用于人体及临床诊断。
027-59234612(+86)
我的积分
注册  /  登录
EIAab
首页  >  酶联免疫试剂盒  >  Human APOBEC3B ELISA Kit
APOBEC3B (基因名), DNA dC->dU-editing enzyme APOBEC-3B (蛋白名), ABC3B_HUMAN.
产品名称:

Human APOBEC3B/ DNA dC->dU-editing enzyme APOBEC-3B ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

A3B, Phorbolin-1-related protein, Phorbolin-2/3

检测方法:
ELISA
特异性:
Natural and recombinant human DNA dC->dU-editing enzyme APOBEC-3B
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human APOBEC3B ELISA Kit
×
Human APOBEC3B ELISA Kit
邮箱 *
消息 *
Please 登录.
产品说明书


通用注释


亚单元:
Homodimer. Interacts with APOBEC3G. Does not interact with APOBEC1.


功能:
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
消息
close_message
产品名称 *
邮箱 *
消息 *
通知
new 留 言
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com