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首页  >  酶联免疫试剂盒  >  Mouse Apbb1ip ELISA Kit
Apbb1ip (基因名), Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (蛋白名), AB1IP_MOUSE.
产品名称:

Mouse Apbb1ip/ Amyloid beta A4 precursor protein-binding family B member 1-interacting protein ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

APBB1-interacting protein 1, Proline-rich EVH1 ligand 1, PREL-1, Proline-rich protein 48, Prel1

检测方法:
ELISA
特异性:
Natural and recombinant mouse Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Mouse Apbb1ip ELISA Kit
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产品说明书


通用注释


亚单元:
Interacts, through the N-terminal Pro-rich region, with the WW domain of APBB1. Interacts with RAP1A, PFN1, VASP and ENAH.


功能:
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.


亚细胞位置:
Cell membrane Peripheral membrane protein Cell projection Lamellipodium Cell junction Focal adhesion Cytoplasm Cytoskeleton Colocalizes with ENA/VASP proteins at lamellipodia tips and focal adhesions, and F-actin at the leading edge. At the membrane surface, associates, via the PH domain, preferentially with the inositol phosphates, PtdIns(5)P and PtdIns(3)P. This binding appears to be necessary for the efficient interaction of the RA domain to Ras-GTPases.


该产品尚未在任何出版物中被引用。

[1].
"RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion."

[2].
"The retinoic acid-responsive proline-rich protein is identified in promyeloleukemic HL-60 cells."

[3].
"A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network."

[4].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[5].
"Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease."

[6].
"A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease."

[7].
"PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins."

[8].
"The DNA sequence and comparative analysis of human chromosome 10."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled."
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