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APBB1IP (基因名), Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (蛋白名), AB1IP_HUMAN.
产品名称:

Human APBB1IP/ Amyloid beta A4 precursor protein-binding family B member 1-interacting protein ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

APBB1-interacting protein 1, Proline-rich EVH1 ligand 1, Proline-rich protein 73, Rap1-GTP-interacting adapter molecule, Retinoic acid-responsive proline-rich protein 1, PREL-1, RIAM, RARP-1, PREL1, RARP1, RIAM

检测方法:
ELISA
特异性:
Natural and recombinant human Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
-
Human APBB1IP ELISA Kit
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Human APBB1IP ELISA Kit
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通用注释


亚单元:
Interacts, through the N-terminal Pro-rich region, with the WW domain of APBB1. Interacts with RAP1A, PFN1, TLN1, VASP, VCL and ENAH.


功能:
Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.


亚细胞位置:
Cell membrane Peripheral membrane protein Cell projection Lamellipodium Cell junction Focal adhesion Cytoplasm Cytoskeleton Colocalizes with ENA/VASP proteins at lamellipodia tips and focal adhesions, and F-actin at the leading edge. At the membrane surface, associates, via the PH domain, preferentially with the inositol phosphates, PtdIns(5)P and PtdIns(3)P. This binding appears to be necessary for the efficient interaction of the RA domain to Ras-GTPases (By similarity).


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