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首页  >  酶联免疫试剂盒  >  Rat Prkab2 ELISA Kit
Prkab2 (基因名), 5'-AMP-activated protein kinase subunit beta-2 (蛋白名), AAKB2_RAT.
产品名称:

Rat Prkab2/ 5'-AMP-activated protein kinase subunit beta-2 ELISA Kit

货号:
-
商标:
EIAab®
监管等级:
别名:

AMPK subunit beta-2

检测方法:
ELISA
特异性:
Natural and recombinant rat 5'-AMP-activated protein kinase subunit beta-2
样品类型:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
样品数据:
研究领域:
Cardiovascular
Rat Prkab2 ELISA Kit
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Rat Prkab2 ELISA Kit
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产品说明书


通用注释


亚单元:
AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3).


功能:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).


亚细胞位置:
N/A


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