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PRKAB2 (GeneName), 5'-AMP-activated protein kinase subunit beta-2 (ProteinName), AAKB2_HUMAN.
Product Name:

Human PRKAB2/ 5'-AMP-activated protein kinase subunit beta-2 ELISA Kit

Cat.#:
-
Brand:
EIAab®
Regulatory Status:
Alternative:

AMPK subunit beta-2

Detection Method:
ELISA
Specificity:
Natural and recombinant human 5'-AMP-activated protein kinase subunit beta-2
Sample Type:
Serum, plasma, tissue homogenates, cell culture supernates and other biological fluids
Sample Data:
Research Area:
Cardiovascular
Human PRKAB2 ELISA Kit
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Human PRKAB2 ELISA Kit
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Product Datasheets


General Annotation


Sub Unit:
AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3).


Function:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).


Subcellular Location:
N/A


This product has not yet been referenced specifically in any publications.
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